describe the structure of a synapse
-presynaptic neurone
calcium ion channels
vesicles with neurotransmitters
-synaptic knob
-synaptic cleft
-postsynaptic neurone
sodium ion channels
-presynaptic and postsynaptic membrane
describe the neuromuscular junction
motor neruone and muscle cell
-presynaptic neurone, synaptic cleft, vesicles with neurotrnsmitters
-sarcolemma (membrane)
-muscle fibre
cholinergic synapse
-action potential opens calcium ion channels
-calcium ions enter
-vesicles with acetylcholine move to and fuse with presynaptic membrane
-acetycholine released and diffuses through synaptic cleft
-binds to receptors on sodium ion channels on postsynaptic membrane
-sodium ions enter and depolarisation occurs
what is spatial summation
many neurones release neurotransmitters to exceed threshold
what is temporal summation
one neurone repeatly releases neurotransmitters over a short period of time to exceed threshold value
why is transmission unidirectional
-onloy presynaptic neurones release acetylchoene
-only postsynaptic neurones have receptors
what do inhibitory synapses do
bind to receptors on chloride ion channels
chloride ions enter and pottassium ions leave causing hyperpolarisation