Syndromes

Question 1

Gorlin Goltz

Answer 1

Basal Cell Nevus Syndrome
Now treatable with Vismodegib
Hedgehog pathway inhibitor

Question 2

Gardner’s Syndrome

Answer 2

epidermal / sebaceous cysts
Bear track CHRPE
familial adenomatous polyposis coli

Question 3

Muir - Torre

Answer 3

Sebaceous adenoCa, keratoacanthoma,Colorectal Ca, GU malignany

Question 4

Gradegnio’s Syndrome

Answer 4

Localized inflammation of the petrous apex
usually from complicated otitis media
CNVII palsy, ipsilateral decreased hearing and facial pain

Question 5

Cowden Syndrome

Answer 5

Tricholemmoma

Breast fibroadenoma and Thyroid CA

Question 6

Carney Complex

Answer 6

Eyelid Myxoma - Cardiac Myxoma, testicular tumour and adrenal hyperplasia