1
Q
Meglitinides - Prandin
A
stimulates release of insulin
2
Q
GLP1 Receptor Agonists - Byetta
A
- Slows gastric emptying
- release insulin when glucose is present
- inhibits release of glucagon
- suppresses appetite
3
Q
Biguanides - Metformin
A
- inhibits glucose production in liver
- sensitizes insulin receptors
- slight decrease in glucose absorption
4
Q
DPP4 inhibitors - Januvia
A
- blocks dpp4/prevents incretin breakdown
- stimulates insulin release when glucose is present
- decreases release of glucagon
5
Q
SGLT2 inhibitors - Invokana
A
blocks reabsorption and increases excretion of glucose by inhibiting sodium glucose co-transporters
6
Q
Alpha-glucosidase inhibitors - Precose
A
delays absorption of carbohydrates
7
Q
TZD’s - Avandia
A
Restores the effectiveness of insulin by:
1. decreases insulin resistance
2. promotes glucose uptake by sk muscle and fat cells
3. decreases glucose production by the liver
8
Q
Sulfonylureas - Glynase
A
- stimulates the release of insulin
- decreases glucose production in liver
- Increases tissue responsiveness
- increases use of insulin
