Tabletting Machine

Question 1

What are the two types of interaction upon compaction?

Answer 1

Particle-particle

Particle - metal

Question 2

Describe the following theories: mechanical, intermolecular, liquid surface film

Answer 2

Mechanical interlocking

Contact between new surfaces cause VDWs forces to act

Surfaces melt under applied pressure upon release of pressure the melted material crystallises forming connections between particles

Question 3

What are the 7 stages of tablet formation?

Answer 3

Filling of die 
Particle rearrangement 
Elastic deformation at point of contact 
Fragmentation/ plastic deformation 
Bonding 
Plastic deformation of solid body 
Decompression and ejection