TACE

Question 1

What is TACE

Answer 1

Transarterial
Chemoembolization

Question 2

places chemotherapy and synthetic materials called embolic agents into a blood vessel feeding a cancerous tumor to cut off the tumor’s blood supply and trap the chemotherapy within the tumor

Answer 2

TACE

Question 3

carries blood to the liver from the intestines, spleen, pancreas, and gallbladder

Answer 3

Hepatic Portal Vein

Question 4

Give 5 clinical indications of TACE

Answer 4

• Unresectable hepatocellular carcinoma
• Selective Metastatic disease
• Cholangiocarcinoma
• decreasing liver function
• patient’s daily activity performance capabilities
• lack of microvascular invasion
• limited extrahepatic disease
• isolated or hepatic dominant metastatic deposits

Question 5

give 5 contraindications of TACE

Answer 5

• Extensive tumor infiltration throughout the liver
• Encephalopathy
• Large burden of extra-hepatic metastases
• Liver or renal failure
• Uncorrectable coagulopathy
• Acute Decompensation of baseline liver function
• Iodinated contrast allergies
• Portal Vein Thrombosis

Question 6

This condition refers to low levels of red blood cells, white blood cells or platelets

Answer 6

Sever cytopenia

Question 7

What do you call the condition that refers to low levels of RBC?

Answer 7

Anemia

Question 8

What do you call the condition that refers to low levels of WBC?

Answer 8

Leukopenia

Question 9

What do you call the condition that refers to low levels of platelets?

Answer 9

Thrombocytopenia

Question 10

approaches of TACE

Answer 10

Trans-femoral route (hepatic artery approach)

Question 11

What is the chemotherapy drug used in TACE?

Answer 11

doxorubicin 50 mg, cisplatin 100 mg, 10 ml iodinated non-ionic CM, 20 ml liopodol

Question 12

Give 5 complications of TACE

Answer 12

Generalized abdominal discomfort
Low-grade fever
Nausea
Malaise
Hepatic Insufficiency
Abscess
Biliary necrosis
Tumor rupture
Cholecystitis

Question 13

Aftercare of TACE

Answer 13

• Daily Monitoring of liver and renal function
• Follow-up imaging at 3-16 weeks
• Inspection of pseudo-
  aneurysms

Question 14

Procedure of Tace

Answer 14

1. make a small incision on the femoral artery
2. insert catheter through incision
3. using real time fluoro, guide catheter to tumor
4. Inject die through the catheter to make it easier to visualise the tumor
5. Inject chemotherapy drug to tumor
6. Remove catheter, put bandage over incision