targeted mutations side effects

Question 1

agent causing infusion reaction

Answer 1

amivantamab

Question 2

agent causing ILD, diarrhea, rash

Answer 2

osimertinib

Question 3

agent causing CPK elevations, bradycardia, and hepatotoxicity

Answer 3

alectinib

Question 4

agent causing FEVER

Answer 4

dabrafenib/trametinib

Question 5

agent causing QT prolongation, vision, hyperuricemia, hepatotoxicity, CHF

Answer 5

entrectinib

Question 6

agent causing delirium, memory changes

Answer 6

larotrectinib

Question 7

agent causing muscle pain, ILD, hepatotoxicity, diarrhea

Answer 7

sotorasib

Question 8

agent causing pulmonary toxicity, cardiotoxicity, bone marrow suppression, GI effects

Answer 8

fam-trastuzumab deruxtecan

Question 9

agent causing pulmonary toxicity, cardiotoxicity, bone marrow suppression, neuropathy

Answer 9

ado-trastuzumab emtansine