Latent TB treatment
Isoniazid 9 months
Rifampin 4 months
Give Isoniazid with
Vitamin B6 - decrease peripheral neuropathy
risk factors to get active TB from latent infection
HIV/AIDS immunosuppression - transplant setting - Silicosis - chronic renal failure - recent infection with TB
if you suspect active disease
Do not use a TBST
which drug has little or no activity in high O2 areas, kills dormant bacteria
PZA - activity in low o2 tension
which drug has the best activity in areas of solid caseum or fibrosis?
Rifampin