ACE inhibitors
renal damage
Aminoglycosides
CN VIII
Carbamazapine
neural tube defects, IUGR, craniofacial defects
DES
clear cell adenocarcinoma
lithium
ebstein’s anomaly(atrialized RV)
Valproate
neural tube defects
Warfarin
Bone/opthalmologic abnormalities, hemorrhage
phenytoin
microcephaly, IUGR, fetal hydantoin
alcohol
retardation, microcephaly, holoprosencephaly, fistulas
smoking
preterm labor, IUGR, ADHD
cocaine
addiction, placental abruption
diabetes
caudal regression, neural tube, heart defects