Gamete Formation
46xx (female) or 4bxy (male) determines male or female
Haploid Cells
23 chromosomes from male i female unit to create human (46 chromosomes) 23+23=46
Mitosis
only occurs in non-reproductive cells 2 identical daughter cells
Meiosis
occurs in reproductive (germ) cells 4 unique haploid ‘daughter cells’
Stage 2 of meiosis
isn’t complete in an oocyte until fertilization occurs
Implantation
corpus luteum helps prep the endometrium for implantation
Blastocyst differentiation
Trophoblast : thin outer layer gives rise to embryonic portion of placenta
Blastocele
fluid-filled cavity; becomes the yolk sac
Embryoblast
becomes baby inner cell mass develops into the embryo
Fertilization
occurs in the ampulla of fallopian tube 24-36 hours after ovulation
One Sperm
must break through the Corona radiata ¿ Zona Pellucida activated
Zona Pellucida
prevents other sperm from entering egg fertilize the egg
Conceptus
doesn’t move through fallopian tube= ectopic pregnancy
Fertilization stages
1). Fertilization 2). Zygote (24 hours) 3). Two-Cell stage (30 hours) 4). Four-Cell Stage (day 2) 5). Blastocyst (day 4-5) what implants into uterus 6) implantation of blastocyst (day 6)
Decidua
reaction for fertilization to occur 3 layers: Decidua Basalis, Decidua Capsularis, Decidua Parietalis
Decidua Basalis
area of endometrium that forms maternal portion directly surrounds placenta
Decidua Capsularis
encloses the developing embryo
Decidua Parietalis
lines remainder of endometrial cavity not near placenta or embryo
If pregnancy occurs
endometrium stays decidualized becomes the ‘decidua’→ receptive to implantation
Implantation timing
occurs 6 days after fertilization: occurs 4-10 days
Trophoblast cells differentiation
Cytotrophoblast: inner mass helps to establish blood flow to placenta by invading
Syncytiotrophoblast
outer mass produces pregnancy hormone hCG burrows into endometrial surface produces more progesterone
Development Of Placenta
Chronic villi project from blastocyst into the decidua
Maternal blood flow
flows into spaces between villi j fetal capillaries for umbilical vein