what is tetanospasmin
body cannot stop contracting the muscles
Tetanospasmin process
binds to inhibitory interneurons which prevents the release of glycine which relaxes the muscle, inhiborty neuron releases acetycholine continuous which causes spasms
the progression of tetanus
neck -> arms,legs -> diaphragm, ribs -> death
treatment of tetanus
sedatives, muscle relaxants, penicillin, tetanospasm antitoxin, vaccine boosters every 7-10 years