Thyroid cancer

Question 1

what are the features of papillary thyroid cancer?

Answer 1

70%
Often young females 
Metastasis to cervical lymph nodes 
Thyroglobulin can be used as a tumour marker 
excellent prognosis

Question 2

what are the features of follicular thyroid cancer?

Answer 2

20%
Present as a solitary thyroid nodule 
Middle aged women >50 
Metastasis to lung and bones 
Good prognosis

Question 3

what are the features of medullary thyroid cancer?

Answer 3

5%
part of MEN-2
Calcitonin acts as tumour marker

Question 4

what are the features of anaplastic thyroid cancer?

Answer 4

1%
Common in elderly females 
Not responsive to treatment
Local invasion is common 
Poor prognosis

Question 5

what are the features of lymphoma thyroid cancer?

Answer 5

Rare

Associated with Hashimoto’s thyroiditis

Question 6

presenting symptoms of thyroid cancer?

Answer 6

• Slow-growing neck lump
• Discomfort swallowing
• Hoarse voice

Question 7

signs of thyroid cancer?

Answer 7

• Cervical lymphadenopathy

Question 8

what bloods should be done for thyroid cancer?

Answer 8

o	TFTs 
o	Bone profile  
o	Tumour Markers 
•	Thyroglobulin - papillary and follicular  
•	Calcitonin - medullary

Question 9

gold standard for thyroid cancer?

Answer 9

• Fine-Needle Aspiration