Thyroid Hormones

Question 1

Thyroglobulin is a large protein with about …….. Amino acid and a weight of ……..

Answer 1

5000 amino acid
660kDa

Question 2

Thyroglobulin contains about ……. Glycoprotein

Answer 2

10 % glycoprotein

Question 3

Thyroglobulin contains……. Number of tyrosine residue but only ………. Can be iodised

Answer 3

115 tyrosine
35

Question 4

Patient with iodotyrosyl coupling defect an inborn error is administered?

Answer 4

T4 supplement produced by recombinant DNA

Question 5

The human thyroid secrets about
…..,… Of T4
………. Of T3
……..of RT3

Answer 5

80 g( 103nmol)
4g(7nmol)
2g(3.5nmol)

Question 6

Uncoupling of thyroglobulin and T4 is done by?

Answer 6

Iodotyrosine protease