Tolerance

Question 1

Tolerance (p114)

Answer 1

Decreased effects of the same dose over time

Pt reports he used to feel pain relief with one pill but now needs 3 pills to achieve the same level of relief due to taking medication for 5 years

Question 2

Kindling p174

Answer 2

some regions of the brain to react to repeated low level bioelectrical stimulation by progressively boosting synaptic discharges, thereby lowering seizure thresholds. Benzos can increase risk of seizures

Question 3

Addictions p299

Answer 3

compulsive substance use despite harmful consequences

Question 4

Potency p113

Answer 4

amount of drug required to produce an effect of given intensity