ADP ribosylation of EF-2
Diphtheria toxin and Exotoxin-A of Pseudomonas
Depolymerization of actin-cytoskeletal structural disruption
B-component of C. difficile A-B toxin
Lecithinase (Phospholipase)-cell membrane disruption
Cl. perfringens
Inhibition of ACh release due to cleavage of SNARE
Botulinum toxin
Inhibition of inhibitory NTs- Glycine and GABA
Tetanospasmin
Increase cAMP
Cholera, Anthrax, ETEC (LT- heat labile), Pertussis, Compylobacter jejuni, B. cereus
Increase cGMP
ETEC (ST-heat stable), Yersinia enterocolitis