what is transfer Factor ?
the rate at which a certain gas will diffuse from alveoli into blood - Carbon monoxide is used to TEST the rate of diffusion
Results given as total gas transfer
causes of raised TLCO ?
Convalescent asthma - NOT ACUTE ASTHMA
pulmonary haemorrhage - WEGNER’S disease and Goodpasture’s
Left to right cardiac shunt
Polycethemia
Hyperkinetic states
Male , exercise
Causes of lower TLCO ?
pulmonary fibrosis - abestosis
pneumonia
PE
pulmonary edema
emphysema
anaemia
Low cardiac output