Transfusion

Question 1

Transfusion modification
Leukoreduction
What is leukoreduction?

Answer 1

Reduces the # of WBC present in the RBC or plt product

Question 2

Transfusion modification
Leukoreduction
What can leukoreduction do?

Answer 2

Reduces class IHLA alloantibody production and subsequent plt transfusion refractoriness;
Febrile nonhemolytic transfusion reactions;
Transmission of CMV

Question 3

Transfusion modification
Leukoreduction
Can leukoreduction reduce transfusion-associated GVHD?

Answer 3

No.