Translocations

Question 1

Translocation found in Burkitt’s lymphoma

Answer 1

• t(8;14)

- c-myc (8) and heavy-chain Ig (14)

Question 2

Translocation found in mantle cell lymphoma

Answer 2

• t(11;14)

- cyclin D1 (11) and heavy-chain Ig (14)

Question 3

Translocation found in follicular lymphoma

Answer 3

• t(14;18)

- heavy-chain Ig (14) and bcl-2 (18)

Question 4

Translocation found in ALL

Answer 4

• t(12;21)

Question 5

Translocation found in AML

Answer 5

• t(15:17)

Question 6

Translocation found in CML

Answer 6

• t(9;22) - Philadelphia chromosome

- bcr (9) and abl (22) fusion

Question 7

Translocation found in Ewing Sarcoma

Answer 7

-t(11;22)

Question 8

Translocation found in anaplastic large cell lymphoma

Answer 8

• t(2;5)

Question 9

Translocation found in mucosa-associated lymphoid tissue (MALT) lymphoma

Answer 9

• t(11:18)