Farmacología > Tratamiento para tuberculosis > Flashcards

Tratamiento para tuberculosis Flashcards

(10 cards)

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1
Q

Tx de TB (4)

A

Isoniazida
Rifampicina
Etambutol
Pirazinamida

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2
Q

Mecanismo de acción de isoniazida

A

Inhibe síntesis de ácido micólico

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3
Q

EA de isoniazida (2)

A

Hepatotoxicidad
Neuropatía periférica

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4
Q

¿A qué se debe la neuropatía periférica por isoniazida?

A

Disminución de vitamina B6

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5
Q

Mecanismo de acción de rifampicina

A

Inhibe a la RNA polimerasa

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6
Q

¿A dónde tiene permeabilidad de rifampicina?

A

SNC

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7
Q

EA de rifampicina (4)

A

Resistencia
Hepatotoxicidad
Hipersensibilidad
Líquidos naranjas

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8
Q

Mecanismo de acción de etambutol

A

Inhibe a la arabinosil transferasa

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9
Q

EA de etambutol (4)

A
  • Neuritis óptica
  • Alteración en la visión
  • Convulsiones
  • Hiperuricemia y gota
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10
Q

EA por pirazinamida (2)

A
  • Artralgias
  • Hiperuricemia y gota
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