Trigger - poison

Question 1

isoniazid induced seizures require what

Answer 1

pyridoxine

Question 2

calcium oxalate is associated with what poisoning

Answer 2

ethylene glycol/antifreeze

Question 3

when do we use pyroxidine

Answer 3

isoniazid induced seizures

Question 4

In what circumstances can activated charcoal be used after 1 hr

Answer 4

• toxins that slow GI transit
• toxins that form bezoars

Question 5

what substances is acitvated charcoal not useful for

Answer 5

• metals (lithium, iron, lead)
• corrosives
• alcohols

Question 6

if a patient OD’d on a cholinergic medication, you would expect their pupils to….

Answer 6

constrict!!! (both start w c:))

Question 7

What is the CI for gastric irrigation

Answer 7

• absent bowel sounds
• suspected ileus/obstruction

Question 8

when is multidose activated charcoal indicated

Answer 8

inegstions of toxic levels of:
* carbamazepine
* dapsone
* phenobarb
* quinine
* theophylline

Question 9

what position should you put patients in for a gastric lavage? what do you use for a gastric lavage?

Answer 9

• left lateral decubitus w head of bed tilted down
• Orogastric tube
• 200ml of warm tap water put into stomach and reomoved via gravity or suction

Question 10

what is the tx for moderate/severe salicylate toxicity

Answer 10

urinary aklalization

IV admin of sodium bicarb +/- KCl
Urine pH goal of 7.5-8.5
keep serum K+ at 4-4.5

Question 11

for overdoses on drugs that are protein bound or lipid soluble, what is the most effective treatment

Answer 11

hemodialysis

Question 12

for overdoses on drugs that are water-soluble and have low molecular weight what is the most effective treatment

Answer 12

Hemoperfusion

Question 13

when do you use BZDs in poisoned patients?

Answer 13

when they have HTN and agitated.

Question 14

If a patient who has been poisoned and has HTN with a risk of end organ damage what drugs should you use? what drug should you avoid?

Answer 14

Use:
* CCB
* Phentolamine
* Labetalol
* nitroprusside

avoid BB in sympathomimetic toxicity (idk)