TSM 1.14

Question 1

what is neurapraxia?

Answer 1

• damage is minimal

- axons remain intact but conduction ceases due to local ischemia and demyelination

Question 2

what is axonotmesis

Answer 2

• axon damaged by compression or traction

- the investing sheaths remain intact

Question 3

what is neurotmesis?

Answer 3

entire nerve is completely divided

Question 4

what inhibts axon growth in CNS?

Answer 4

• CNS myelin

Question 5

why CNS cannot have nerve regeneration?

Answer 5

• different myelin
• no axon promoting molecules
• inhibitory molecules present
• GAP 43 has no effect

Question 6

describe axon regneration in PNS?

Answer 6

• motoneurone synthesizes proteins needed for axon growth

- when motor axon sprouts will find array of schwann cells to guide