What antibiotics are used in the initial phase for TB?
RIPE
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
2 months
What antibiotics are used in the continuation phase of TB?
Rifampicin
Isoniazid
4 months
What are the counselling points for rifampicin?
Enzyme inducer - do not use oral contraceptives, insert IUD
Report signs of hepatotoxicity
Colours contacts and urine red/orange
What are the counselling points for isoniazid?
It’s an enzyme inhibitor
Report signs of hepatotoxicity
Can cause peripheral neuropathy - use pyridoxine
What is the main side effect of pyrazinamide?
Hepatotoxicity
What are the counselling points for ethambutol?
Report visual changes immediately