Tuberculosis

Question 1

Hallmark sx of TB

Answer 1

• Fatigue, weight loss, fever, night sweats, productive cough
• Lymphadenopathy
• Travel to endemic area

Question 2

What will CXR show for TB?

Answer 2

Pulmonary opacities

Question 3

What is needed to confirm TB?

Answer 3

Sputum cultures

Question 4

What bacteria causes TB?

Answer 4

Mycobacterium Tuberculosis

Question 5

What physical findings might you find during exam or TB patients

Answer 5

• dullness w/decreased fremitus
• Posttussive crackles
• Amphorae (hollow breath sounds)

Question 6

What pulmonary signs might you find on examination of a TB patient

Answer 6

Clubbing of fingers

Question 7

How many specimen samples do you need?

Answer 7

3, consecutive morning specimens

Question 8

How much sputum do you need for adequate diagnostic yield?

Answer 8

5-10ml is optimal

Question 9

Treatment for TB

Answer 9

• Isoniazid (INH) 5mg/kg (usually 300mg) QD
• Rafampin 300mg PO BID

Question 10

What should be considered while giving INH?

Answer 10

• Hepatic toxicity
• Place on Vitamin B6 50mg QD
• LFT

Question 11

What should be considered while giving Rifampin?

Answer 11

• Body fluids turn reddish-orange
• Do not wear contacts