U wave definition
small 0.5 mm deflection
same direction as T wave
Normal U wave
same direction as T wave size inversely proportional to HR - increases as HR slows down normal voltage < 25% of T wave max normal amplitude= 1-2 mm
Prominent U Wave
> 1-2 mm
> 25% height of T wave
Prominent U wave DDx
severe Hypokalemia Hypocalcaemia Hypomagnesemia Hypothermia Raised Intracranial pressure L Ventricular Hypertrophy Hypertrophic cardiomyopathy
Prominent U waves: secondary to DRUGS
Digoxin
Phenothiazine
Class Ia antiarrhythmic: quinidine/ procainamide
Class III antiarrhythmic: sotalol/ amiodarone
Inverted U wave
inversion abnormal in lead with upright T wave
negative U highly specific for presence of heart dz
Inverted U causes
Coronary artery disease HTN Valvular Heart Disease Congenital Heart Disease Cardiomyopathy Hyperthyroidism
Inverted U and Chest Pain
very specific Myocardial Ischaemia
earliest marker unstable angina evolving MI
predict ≥ 75% stenosis of LAD/ LMCA & LV dysfunction