1
Q
Drugs associated with cholestasis
A
The following drugs tend to cause cholestasis (+/- hepatitis):
oral contraceptive pill
antibiotics: flucloxacillin, co-amoxiclav, erythromycin*
anabolic steroids, testosterones
phenothiazines: chlorpromazine, prochlorperazine
sulphonylureas
fibrates
rare reported causes: nifedipine
2
Q
Drugs associated with hepatocellular picture
A
The following drugs tend to cause a hepatocellular picture: paracetamol sodium valproate, phenytoin MAOIs halothane anti-tuberculosis: isoniazid, rifampicin, pyrazinamide statins alcohol amiodarone methyldopa nitrofurantoin
3
Q
Drugs associated with cirrhosis
A
Liver cirrhosis
methotrexate
methyldopa
amiodarone
