UTI

Question 1

Bacterial infection of the bladder confined to lower urinary tract is called what?

Answer 1

Acute cystitis

Question 2

Bacterial infection of upper urinary tract is called what?

Answer 2

Acute pyelonephritis

Question 3

What are the 3 criteria for uncomplicated UTIs?

Answer 3

1-Not pregnant
2-Normal urinary anatomy
3-No co-morbidities

Question 4

What are the 6 criteria that would make a patient a complicated UTI case?

Answer 4

1-Pregnant
2-Abnormal urological anatomy
3-Diabetes mellitus
4-Immune compromise
5-Indwelling bladder catheter
6-Male Gender

Question 5

A healthy individual should have what kind of bacterial colonization?

Answer 5

None. Urine should be sterile in a healthy young person

Question 6

85% of bacteria that cause UTIs are what?

Answer 6

Gram negative colonizers of GI tract

*ie. E. Coli, proteus mirabilis, klebsiella pneumoniae

Question 7

Pili, flagella, adhesins, siderophores, toxins and polysaccharide coating on E. Coli are referred to as what?

Answer 7

Virulence factors

*allows it to be uropathogenic

Question 8

Pain or burning with urination (dysuria), increased frequency and urgency of urination and suprapubic pain are symptoms suggesting what?

Answer 8

Cystitis

Question 9

Fever/chills, flank pain, nausea/vomiting plus symptoms of cystitis could suggest what?

Answer 9

Pyelonephritis

Question 10

What 3 things are necessary for a UTI diagnosis?

Answer 10

1-Symptoms
2-Urine culture of 10^5 CFU/mL
3-Evidence of urinary tract inflammation (WBC)

*Positive culture without symptoms is asymptomatic bacteriuria

Question 11

Nitrofurantoin, Trimethoprim-sulfamethoxazole and fosftomycin are all used to treat what?

Answer 11

Uncomplicated cystitis

Question 12

Fluoroquinolones, trimethoprim-sulfamethoxazole and B-lactams are all used to treat what?

Answer 12

Uncomplicated pyelonephritis

Question 13

What are 4 situations in which you would treat asymptomatic bacteriuria with antibiotics?

Answer 13

1-Pregnant
2-Pre-urology procedure
3-Renal transplant
4-Neutropenic

Question 14

How are the symptoms of a catheter associated UTI different?

Answer 14

• Usually lack typical UTI symptoms
• New fever with no other source
• CVA tenderness, flank pain, pelvic discomfort