Uvea

Question 1

Uvea Terminology

Answer 1

Question 2

Heterochromia Iridis (or Iridum)

Answer 2

Question 3

Iris Coloboma

Answer 3

Question 4

Persistent Pupillary Membranes (PPMs)

Answer 4

• PPMs
– Iris-to-iris*
– Iris-to-cornea
– Iris-to-lens
• Cause corneal or lenticular opacity where contact occurs (NOT desirable)

Question 5

Iris Atrophy

Answer 5

• Progressive thinning of the iris
• Scalloped pupil, transillumination defects due to stromal thinning, full-thickness holes
• Common finding in old dogs

Question 6

Uveal Cysts

Answer 6

• Iris or ciliary body cysts
• Benign, usually an incidental finding

Question 7

Inflammation of the Uvea =

Answer 7

Uveitis

Question 8

uvea (meekins)

Uveitis terminology
• Anterior uveitis
• Posterior uveitis
• Panuveitis
• Endophthalmitis
• Panophthalmitis

Answer 8

Question 9

Uveitis Causes

Answer 9

Question 10

uvea (meekins)

Anterior Uveal Tract

Answer 10

Question 11

uvea (meekins)

Signs of Anterior Uveitis

Answer 11

Question 12

uvea (meekins)

Posterior Uveal Tract

Answer 12

Question 13

uvea (meekins)

Signs of ACTIVE Posterior Uveitis

Answer 13

Question 14

uvea (meekins)

Signs of INACTIVE Posterior Uveitis

Answer 14

Question 15

Causes of Uveitis:
There are MANY!
Most common?

Answer 15

IDIOPATHIC

Question 16

uvea (meekins)

• *Causes of uveitis:**
• *ocular manifestations of systemic dz**

Answer 16

Question 17

uvea (meekins)

• *Causes of uveitis:**
• *primary ocular**

Answer 17

Question 18

Uveitis Workup

Answer 18

Question 19

uvea (meekins)

Treatment of Uveitis (general)

Answer 19

• Treat cause if known (Specific)
• In most cases the cause is not known…. (Symptommatic)

Goals of therapy

1. Decrease inflammation
2. Relieve pain
3. Prevent complications of uveitis

Question 20

uvea (meekins)

Anti-inflammatory Therapy

Answer 20

Question 21

uvea (meekins)

Treatment of Uveitis

• systemic immunosuppresives
• antimicrobials

Answer 21

Question 22

uvea (meekins)

• *Treatment of Uveitis**
• *• Mydriatic/cycloplegic**

Answer 22

Question 23

Sequelae of Uveitis

Answer 23

Question 24

Uveal Neoplasia

Answer 24

Question 25

Treatment of Uveal Tumors

Answer 25

* Thorough physical examination * Thoracic radiographs and abdominal radiographs/ultrasound – Especially in cats with FDIM * Local treatment – Excision or laser (focal lesions) * Enucleation & histopathology – Extensive primary tumors – Inflamed or glaucomatous eyes * Chemotherapy – Ocular metastasis from distant site

Question 26

# uvea (meekins) **_Summary_** • Common clinical signs of anterior uveitis: • Inactive posterior uveitis = • Most common diagnosis = • Treatment goals for uveitis include…

Answer 26

* Common clinical signs of anterior uveitis: **– Aqueous flare, miosis, hypotony** * Inactive posterior uveitis = **chorioretinal scars (tapetal hyperreflectivity)** * There are many possible causes of uveitis in small animals – Most common diagnosis = **idiopathic** * Treatment goals for uveitis include **decreasing inflammation, relieving pain, and preventing complications/sequelae**