Uworld - Screening/development

Question 0

In an emergency, if peripheral venous access not available, next step?

Answer 0

Intraosseous access

Question 1

Screening test for PKU?

Answer 1

Guthrie test – presence of phenylalanine products in your

Question 2

Infant with Turner’s – cause of edema?

Answer 2

Lymphatic dysgenesis

Question 3

Patient with down syndrome who presents with ataxia, incontinence, and positive Babinski – most likely diagnosis?

Answer 3

Atlantoaxial instability

Question 4

Difference glucose-6-phosphatase deficiency versus debranching enzyme deficiency?

Answer 4

Lactic acidosis, hyperuricemia, hyperlipidemia, doll-like face

Elevated transaminases, ketosis, normal kidneys/Uric acid/lactate

Question 5

Small for gestational age infants are at risk for what complications?

Answer 5

1. meconium aspiration
2. hypothermia
3. hypoglycemia
4. hypocalcemia
5. polycythemia

Question 6

Time course – breast-feeding jaundice versus breast milk jaundice?

Answer 6

First week of life versus extending into 3+ weeks of life

Question 7

Newborn with surfactant deficiency – likely due to?

Answer 7

Maternal diabetes, prematurity

Question 10

Facial dysmorphisms in fetal alcohol syndrome?

Answer 10

1. Small palpebral fissures
2. Smooth philtrum (vertical groove above upper lip)
3. Then Vermilion border (thin upper lip)

Question 11

Only absolute contraindication for breast-feeding in infants?

Contraindications for breast-feeding in mothers?

Answer 11

Galactosemia

TB, HIV, herpetic breast lesions, varicella, chemo/drugs of abuse

Question 12

Facial features in:

1. Fetal alcohol syndrome
2. Down syndrome
3. Fragile X

Answer 12

1. Smooth philtrum, thin Vermilion border, small palpebral fissures, microcephaly
2. Flat face, slanted palpebral fissures, small low-set ears
3. Long/narrow face, prominent forehead/chin, large ears, macrocephaly

Question 13

Marfan’s versus homocystinuria?

Answer 13

Homocystinuria = Marfan’s + thromboembolic event

Question 14

Colics - start/end ages?

Answer 14

3 weeks to 4 months of age

Question 15

Down syndrome – most common cardiac abnormality?

Answer 15

AV Canal defect (endocardial cushion defect)

Question 16

McCune-Albright syndrome characterized by?

Answer 16

Precocious puberty, café au lait spots, multiple bone defects (breakages etc)