What is immunological memory?
The process by which the immune system “remembers” a specific antigen after an initial exposure.
What is active immunization?
Exposing an individual to an antigen to stimulate their own immune system to develop protective immunity and a memory response.
What is passive immunization?
Introducing preformed antibodies to provide immediate, temporary protection without creating a memory response.
How can active immunization occur?
Through natural infection or vaccination.
What is the key difference between active and passive immunization?
Active immunization creates a memory response, while passive immunization does not.
What is a prime example of passive immunization?
Maternal antibodies passed to a baby.
What is immunological memory?
The process by which the immune system “remembers” a specific antigen after an initial exposure.
What is active immunization?
Exposing an individual to an antigen to stimulate their own immune system to develop protective immunity and a memory response.
What is passive immunization?
Introducing preformed antibodies to provide immediate, temporary protection without creating a memory response.
How can active immunization occur?
Through natural infection or vaccination.
What is the key difference between active and passive immunization?
Active immunization creates a memory response, while passive immunization does not.
What is a prime example of passive immunization?
Maternal antibodies passed to a baby.
What is an attenuated vaccine?
A vaccine containing a live, but non-pathogenic, version of an organism.
What is a key benefit of attenuated vaccines?
They often don’t require boosters and stimulate both cellular and humoral immunity.
What is a risk of attenuated vaccines?
They may rarely revert to a pathogenic strain or cause disease in an immunosuppressed person.
What is an inactivated vaccine?
A vaccine made from a “killed” organism via chemical inactivation or radiation.
What do inactivated vaccines typically require?
Multiple boosters.
What is a toxoid vaccine?
A vaccine made from inactivated bacterial toxins.
What is an example of a toxoid vaccine?
Tetanus and diphtheria vaccines.
What are purified macromolecule (subunit) vaccines?
Vaccines that use only a part of the microbe, such as a protein or polysaccharide.
What are nucleic acid-based vaccines?
Vaccines that inject a gene (DNA or mRNA) that codes for an antigenic protein.
What are examples of nucleic acid-based vaccines?
The Pfizer and Moderna COVID-19 vaccines.
What disease was officially eradicated in 1977 due to vaccination efforts?
Smallpox.
Why was the oral polio vaccine (OPV) so effective?
It protected the individual and also prevented person-to-person spread.