Vaccinations

Question 1

What are the main aims of vaccinations?

Answer 1

Prevent morbidity/death from preventable diseases

Question 2

Name 4 examples of live vaccinations

Answer 2

BCG
Varicella
MMR
Yellow fever

Question 3

Name 3 examples of inactivated organism vaccines

Answer 3

Typhoid
Pertussis
IPV

Question 4

Name 2 inactivated toxin vaccines

Answer 4

Tetanus

Diphtheria

Question 5

Name 2 organism component vaccines

Answer 5

Influenza

Pneumococcal

Question 6

Advantages of live vaccines

Answer 6

• Single dose sufficient to induce long term immunity

- strong immune response evoked

Question 7

Disadvantages of live vaccines

Answer 7

• can become virulent
• possible contamination
• contraindicated in immunosuppressed
• Interference by viruses/vaccines/passive antibodies
• poor stability

Question 8

Advantages of attenuated/inactive vaccines

Answer 8

• Stable

- Unable to cause infection

Question 9

Disadvantages of Attenuated/inactive vaccines

Answer 9

• Not as long term (shorter term)

- Not as powerful immunity evoked - multiple doses required