Antibiotics > Vancomycin > Flashcards

Vancomycin Flashcards

(10 cards)

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1
Q

moa

A

inhibits cell wall synthesis

targets transglycosylation reaction

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2
Q

pharmacokinetics

A

highly water soluble

poor oral absorption

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3
Q

indication for oral vancomycin

A

pseudomembranous colitis

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4
Q

resistance

A

modification of d-ala d-ala terminus

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5
Q

adverse reaction when combined with aminoglycosides

A

ototoxicity

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6
Q

adverse reaction when combined with NSAID

A

nephrotoxicity

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7
Q

adverse reaction when combined with loop diuretics

A

ototoxicity

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8
Q

caused by rapid vancomycin infusion causing increased histamine release

A

red man/ red neck syndrome

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9
Q

indications

A

MRSA
acute bacterial endocarditis
meningitis
septicemia

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10
Q

other drugs that targets cell wall or cell membrane

A

BacitFosCycloDap

bacitracin
Fosfomycin
cycloserine
daptomycin

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