Vancomycin antibiotic
Not routinely used, binds to D-ala on PDG precursors to prevent cross-linking
Virulence factor of VRE
Frequent and efficient conjugation that can even be observed in real time during outbreaks
VRE G+ vs G-
Gram positive
VRE plasmids
Highly conjugative
- Formerly chromosomal DNA that VRE happily integrates into their genome
Consequence of the genetic capacity of VRE
Resistence acquisition via natural competence and efficient DNA sampling