GPCRs coupled to vasoconstriction
-a1-adrenergic*
-angiotensin 1
-andothelin A
-vasopressin 1
vasoconstriction mech
-Ca calmodulin
-=myosin LC
+ actin = contractionk
therapeutic use of vasoconstrictors
–shock (anaphylactic, brain trauma, hemorrhagic)
-anesthesia
-chronic orthostatoc hypotension
-reduce blood flow
-hemostasis during surgery
-decongestants
Vasoconstrictors
-epinephrine
-phenylephrine
-midodrine
-droxidopa