Vasodilators

Question 1

3 Main uses of Calcium Blockers

Answer 1

1. HTN
2. SVT
3. Angina

Question 2

Hydralazine MOA

Answer 2

Vasodilates via cGMP

Question 3

In regards to smooth muscle, De-Phosphorylating MLCK results in ______

Answer 3

Relaxation

Question 4

5 Dihydropyridine Calcium Blockers

Answer 4

1. Nifedipine
2. Amlodipine
3. Clevidipine
4. Nicardipine
5. Nimodipine

Question 5

2 Non-Dihydropyridine Calcium Blockers

Answer 5

1. Verapamil

2. Diltiazem

Question 6

Name the Inorganic NO Donor

Answer 6

Sodium Nitroprusside

Question 7

Never Use Nitroglycerine with ____ Inhibitor

Answer 7

PDE5

Question 8

In regards to smooth muscle, Phosphorylating MLCK results in ______

Answer 8

Contraction

Question 9

2 Main side-effects of Sodium Nitroprusside

Answer 9

1. Produces Methemoglobin (left shift)

2. Produces Cyanide

Question 10

Aside from constipation, 3 Main Calcium blocker toxicities

Answer 10

1. Hypotension
2. Bradycardia
3. AV block

Question 11

Nifedipine, Amlodipine, Clevidipine, Nicardipine, and Nimodipine are all ________, which is a class of _______ that only act on the vasculature

Answer 11

• Dihydropyridines

- Calcium Channel Blockers

Question 12

Avanafil, Sildenafil, and Tadalafil are all _________

Answer 12

PDE5 inhibitors
(inhibit breakdown of cGMP)

Question 13

2 Main contraindications of Calcium Blockers

Answer 13

1. AV Block

2. Wolf Parkinson White with A-Fib

Question 14

Hydralazine increases _____ to vasodilate and is great for HTN in pregnancy.

Answer 14

Hydralazine

Question 15

Verapamil and Diltiazem are both non-_______ which are classes of _______ that act both on the heart and the vasculature

Answer 15

• Non-Dihydropyridines

- Calcium Channel Blockers

Question 16

Sodium Nitroprusside doesn’t need to be activated to produce ______

Answer 16

Nitrous Oxide

Question 17

2 Organic NO Donors

Answer 17

1. Isosorbide Dinitrate

2. Isosorbide Mononitrate

Question 18

Isosorbide Dinitrate or Mononitrate are acted upon by enzymes to produce _____ Organically.

Answer 18

Nitrous Oxide