Victoza

Question 1

What percentage of the US population over age 65 has diabetes?

Answer 1

more than 25%

Question 2

What percentage of patients in the LEAD trials were 65 years or older?

Answer 2

20%

Question 3

What percentage of patients considered the Victoza pen easy to learn when demonstrating into a pillow?

Answer 3

90%

Question 4

Why should Victoza be considered for Medicare Part D patients with type 2 diabetes?

Answer 4

1. low rate of hypo
2. works in a glucose dependent manner and is dosed once daily, independent of meals
3. metabolized endogenously by the body with no major target organ for elimination
4. is approved for use with basal insulin
5. no dosage adjustment needed in patients with renal or hepatic impairment

Question 5

What was the average A1c reduction in patients with A1c of 8.5% to 9.0% when 1.8 mg Victoza was added to metformin? compared to Januvia?

Answer 5

1. 56% for Victoza
2. 97 for Januvia

Question 6

What was the average A1c reduction in patients with A1c of 8.0%-8.5% when 1.8 mg Victoza was added to metformin? compared to Januvia?

Answer 6

1. 31% for Victoza
2. 63% percent for Januvia

Question 7

What was the average A1c reduction in patients taking 1.8 mg Victoza when added to metformin? compared to Januvia?

Answer 7

1. 01% for Victoza
2. 37% for Januvia

Question 8

What percentage of patients achieved an A1c goal of 7.0% when Victoza or Januvia was added to metformin?

Answer 8

Januvia: 27%

Victoza 1.2 mg: 50%

Victoza 1.8 mg: 63%

Question 9

What was the average weight loss seen with Victoza 1.8 mg compared to 1.2 mg or Januvia?

Answer 9

1. 8: -8.1 lb
2. 2: -6.1 lb

Januvia 100mg: -2.6 lb