viral replication

Question 1

what are the different structures of a virus?

Answer 1

cylindrical
icosahedral
complex
-enveloped vs non-enveloped

Question 2

what group and type of structure does the herpesviridae family have?

Answer 2

dsDNA group 1
icosahedral and enveloped

Question 3

what does valacyclovir do?

Answer 3

completely inhibits and inactivates viral- DNA polymerases preventing further viral DNA synthesis without affecting normal cellular processes

Question 4

what are the three requirements for successful infection?

Answer 4

1. viral incoculum of sufficient size
2. accessible cells that are both susceptible and permissive
3. local antiviral defense absent or overcome

Question 5

what is the incubation period?

Answer 5

initial period before symptoms are obvious
-virus may or may not be transmitted

Question 6

what virus can be transmitted during the incubation period?

Answer 6

SARS-CoV-2

Question 7

what causes the symptoms of a viral infection? (causing viral disease)

Answer 7

viral replication occurs in the presence of an immune response aimed at preventing viral replication

Question 8

what is viral pathogenesis determined by?

Answer 8

-interaction with specific host
-immune escape
-host immune response causing pathology
-cellular transformation (growth)

Question 9

what is a permissive cell?

Answer 9

cell that has capacity to replicate virus- may to may not be susceptible

Question 10

what types of cells can take up a virus particles and replicate it?

Answer 10

susceptible and permissive cells

Question 11

Answer 11

Question 12

what is virulence and what is it determined by?

Answer 12

-the capacity to cause damage to the host
-determine by both the host and the virus

Question 13

viral virulence

Answer 13