Can viruses reproduce by themselves?
No
They are obligate intracellular parasites
How may viruses be biochemically classified?
RNA vs DNA
Then enveloped vs naked
Name some enveloped DNA viruses:
Hep. B
Herpesviruses
Smallpox
Name some naked DNA viruses:
Papillomavirus
Name some enveloped RNA viruses:
Rubella Rotavirus HIV Coronavirus Ortho/paramyoxoviruses
Name some naked RNA viruses:
Picornaviruses
What is the baltimore classification?
A method of classifying viruses based on their genome and therefore their method of reproduction
What is the host range of a virus?
For a virus to infect a cell, the cell must have a complementary receptor
The range of cells a virus may infect is its host range
What is a viral capsid?
A protein outer coat that protects the genome
What are the two basic capsid structures?
Helical and isochedral
How may a virus cause cancer?
Turning on (or bringing) oncogenes Inactivating TSGs
e.g HPV (especially HPV-16 and HPV-18) produces E6/E7 proteins, which suppress the action of p53 and pRB.
