Viruses

Question 1

DNA viruses

Answer 1

Hepadnavirus, Herpesvirus, Adenovirus, Parvovirus, Papovavirus, Poxvirus

Question 2

Hepadnaviruses

Answer 2

HBV

• acute or chronic hepatitis
• vaccine available
• has reverse transcriptase but NOT retrovirus

Question 3

Herpesviruses

Answer 3

• HSV-1: oral (some genital) lesions, keratoconjunctivitis
• HSV-2: genital (some oral) lesions
• • VZV: chickenpox, zoster, shingles
• EBV: mononucleosis, Burkitt’s lymphoma
• CMV: infection in immunocompromised, esp transplant recipients; congenital defects
• HHV-6: roseola (exanthem subitum)
• HHV-8: Kaposi’s sarcoma-associated herpesvirus (KSHV)

Question 4

Adenovirus diseases

Answer 4

• febrile pharyngitis – sore through
• pneumonia
• conjunctivitis

Question 5

Parvovirus disease

Answer 5

B19 virus – aplastic crisis in sickle cell disease, “slapped cheeks” rash– erythema infectiosum (fifth disease), hydrops fetalis

Question 6

Papovaviruses

Answer 6

• HPV- warts, CIN, vervical cancer

- JC- progressive multifocal leukoencephalopathy (PML) in HIV

Question 7

Poxviruses

Answer 7

• Smallpox, although eradicated, could be used in germ warfare
• Vaccinia- cowpox (milkmaid’s blisters)
• Molluscum contagiosum

Question 8

RNA viruses

Answer 8

Picomavirus, Calciviruses, Reoviruses, Flaviviruses, Togaviruses, Retroviruses, Coronaviruses, Orthomyxoviruses, Paramyxoviruses, Rhabdoviruses, Filoviruses, Arenaviruses, Bunyaviruses, Deltavirus

Question 9

Hepadnavirus

Answer 9

Envelope
DS-partial circular
- HBV-- acute/chronic hep, 
- vaccine
- has reverse transcriptase but not retrovirus

Question 10

Herpesvirus

Answer 10

enveloped, DS-linear

- HSV1, HSV2, VZV, EBC, CMV, HHV-6, HHV-8

Question 11

Adenovirus

Answer 11

no envelope, DS - linear

- febrile pharyngitis, pneumonia, conjunctivitis (pink eye)

Question 12

Parvovirus

Answer 12

No envelope, SS-linear (-)

• smallest DNA virus
• B19 virus– aplastic crises in sickle cell disease, “slapped cheecks” rash-erythema infectiosum (fifths disease), hydrops fetalis

Question 13

Papovavirus

Answer 13

No Envelope, DS-circular

• HPV - warts, CIN, nervical cancer
• JC- progressive multifocal leukoencephalopathy (PML) in HIV

Question 14

Poxvirus

Answer 14

envelope, DS-linear
largest DNA virus
- smallpox, vaccinia, molluscum contagiosum

Question 15

which RNA viruses have envelope

Answer 15

ALL except Picomaviruses, calciviruses, reoviruses