Vegan, Goat Milk, associated methylmalonic acidemia/homocystinuria, megaloblastic macrocytic anemia hypersegmented neutrophils
Vitamin B12 Def
Anemia reticulocytosis, recommended to give with iron to protect from iron-induced hemolysis
Vitamin E Def
Carboxylation prothrombin, important for coagualtion, low GI microorganisms, Maternal meds effect (anti-TB, anti-seizures, warfarin), breastfed, IVH
Vitamin K Def
Lung growth, photophobia, conjunctivitis, abnormal bone formation/tooth enamel
Vitamin A Def
Beriberi (fatigue, constipation, cardiac failure); associated pyruvate dehydrogenase def & maple syrup disease
B1 Thiamine
FTT photophobia/blurred vision, dermatitis, mucositis, associated glutaric aciduria type 1
B2 Def Riboflavin
Dermatitis, anemia, seizures associated homocystinuria
B6 Def Pyridoxine
Alopecia, dermatitis, scaling, seborrhea; Associated biotinidase def, propionic acidemia, betamethycrotonyl glycinuria
Biotin Def
Poor wound healing bleeding gums; asscoaited with transient tyrosinemia
Vitamin C def
regulates glucose levels; role in insulin metabolism
Chromium
hemoglobin formation, RBC production, absorption iron
Copper
Duodenum/proximal jejunum, vitamin C enhances absorption, component of Hb
Iron
Enzyme activation superoxide dismutase, normal bone structure
Manganese
cofactor glutamine peroxidase, associated cardiomyopathy if deficient
Selenium
FTT, alopecia, diarrhea, dermatitis perianal, nail hypoplasia
Acrodermatitis enteropathic = Zinc Def
Vitamin lost in TPN or affected by lightq
Vitamin A
What vitamins should be increased/decreased in TPN in cholestasis
Decrease Manganese and Copper; Increase Zinc
What vitamins should be increased/decreased in TPN in renal insufficiency
Decrease chromium and selenium
