Mis c criteria
Mm gcs
Mucocutaneius
Myocardial Dysfn
Coagulopathy
GI
Shock or hypotension
Note recent Covid 19 or contact needed for dx
Tier one screening for misc
Crp>5 or esr>40
And at least one: alc < 1000
Pl< 1.5 lac
N<135
Neutrophilia
Hypoalb
Tier 2 for misc
Cardiac tests
Inflammatory markers other than esr and crp
SARS cov 2 serology
Misc treatment
If with shock or mods give-
Ivig 2g/kg/d
Anti microbial empirical
If methylpredni 2mg/kg/day
Without shock
I’ve methylpredni same dose as above
Kawasaki phenotype
Ivig and mwthylpredni
Masks usage
Less than five yrs no need
After twelve yrs like adults
Maha is
TTP AND HUS
Here bt is increased but pt and aptt is n
Megakaryocytes increased in bm biopsy
In maha ie ttp and hus production of ——————-microthrombi
Plt microthrombi
Note in plt fibrin microthrombi is in dic
Fat rn!
Fever anemia thrombocytopenia renal failure neuro probs
Congenital absence of adams13
Upshaw Shulaman disease
Dmt1 aka
Nramp 2
M.c clinical feature in s cell trait is
Isosthenaria due to dilute or concentrate urine f
Due to Occlusion of vasa recta
Another clinical feature is painless hematuria due to papillary necrosis
Mc cytogenetic abnormality in mds
Deletion 5q
IPSS PROSTATE SCORING SYSTEM STORAGE AND VOIDING SYMPTOMS
Storage symptoms
FUN
FREQUENCY
URGENCY
NOCTURIA
VOIDING
WUSI
WEAKENED URINARY STREAM
INTERMITTENCY
INCOMPLETE BLADDER EVACUATION
STRAINING
NF1 criteria
Loss of fn mutation of tsg neurofibromin
2 at least of seven criteria positive
- One plexiform nfoma or two or more nfoma
- Mc t.or optic glioma present
- Cafe au lair spot 6 or more
- Freckling in inguinal or a Iola
- Two or more iris lisch nodule
- Long bone cortical thinning, sphenoid dysplasia etc bone lesions
7.first degree relative
Leuconychia seen in
Hypoalb condns like pem renal failure
Liver failure
Cardiac failure
Could be zn dfcy
Retinoids
Pilocarpine
Cytotoxic drugs
Steroids
Skin ds Like
Alopecia areata
Sle
E multiforme
Nmo is mcly seen in
Middle aged women
Antiaq o 4 ab
It shows
Area postrema sd so symps like vomiting and intractable hiccups present
Encephalopathy
Hypothal prob causing endocrinopathies
Tt by steroids and mmf for pxic
New
Eculizumab
Satralizumab
Enebilizumab
Ai encephalitis shows
Anti nmda ror abs
Cough with brown expn and finger in glove appnce
Abpa
In pericardial effusion due to large compression there is dullness at
Lt post lung fields grt ewarts or auenbruggers sign esp on percussion
