Level 1/Step 1 > W5D2 > Flashcards

W5D2 Flashcards

(52 cards)

Study These Flashcards
1
Q

40F
headaches + insomnia + diaphoresis + unintentional wt loss

neoplastic mass = excessive hormone excretion

Tumor cells = electron-dense + membrane secretory granules

IH = synaptophysin + chromogranin + neuro-specific enolase

A

Pheochromocytoma

headaches + insomnia + diaphoresis + unintentional wt loss = catecholamine secretion

IH = synaptophysin + chromogranin + neuro-specific enolase = MEN2A/B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

32M
Self-limiting watery diarrhea post travels

A

Enterotoxins
E. coli = promotes fluid + electrolyte secretion from intestinal epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

9month
High fever breaks
rash

A

HHV3
Roseola

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

9month
cough, coryza, conjunctivitis
Koplik spots

A

Measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

9month
rash started on face and has spread to trunk

A

Rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Linkage disequillibrium

A

inherited haplotype more or less often than expected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

22F
Ab pain
tingling in limbs
anxiety + difficulty concentration + insomnia

Tx: heme preparation

Dx

A

Acute intermittent porphyria

5P’s
Painful ab
Port-wine pee
Polyneuropathy
Psychological disturbances
Precipitants = ALA increased + CYP inducers + EtOH

MOA: precipitants or congenital (AD - porphobilinogen deaminase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

64M
LE pain + swelling + redness
100.4F
erythema = midcalf w/ indistinct border
neutrophilic leukocytosis

Dx

A

Cellulitis =

nonpurulent cellulitis = B-hemolytic streptococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Nerve that is irritated
external auditory canal - close contact with posterior wall

A

Vagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Nerve that is irritated
external auditory canal - excluding the posterior wall

A

mandibular branch of trigeminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

depression of the nasal bridge
bulging forehead
short upper & lower extremities
normal torso

A

Achondroplasia

AD - FGFR3 gene (chondrocytes)

endochondral ossification = long bones affected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Congenital rubella sx

A

Growth restriction
Sensorineural hearing loss
Heart + Eye + CNS issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Congenital rubella syndrome prevention

A

Maternal LIVE attenuated vax before conception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

52F
B/L tremor
Mother had a similar issue

A

Essential tremor (AD) improves w/ EtOH consumption

Tx: Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Sjogren syndrome increases the risk of

A

Non-Hodgkins lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Scleroderma increases the risk of

A

glomerulonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Single-stranded DNA binding protein

A

Stabilization of unwound template strands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

DNA polymerase III

A

DNA synthesis (5′ → 3′ polymerase activity)
Proofreading (3′ → 5′ exonuclease activity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

DNA polymerase III DNA synthesis

A

5′ → 3′ polymerase activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

DNA polymerase III Proofreading

A

3′ → 5′ exonuclease activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DNA polymerase I

Study These Flashcards
A

Same as DNA polymerase III
Removal of RNA primer (5′ → 3′ exonuclease activity) & replacement with DNA

21
Q

DNA polymerase I Removal of RNA primer

Study These Flashcards
A

5′ → 3′ exonuclease activity

22
Q

Bordetella pertussis pathogenesis

Study These Flashcards
A

Tracheal cytotoxin = destroys ciliated epithelial cells
pertussis toxin = AB toxin = increase cAMP = inhibits phagocytosis = lymphocytosis

23
Q

tx for neonatal w/d from opioids

24
lowering alpha from .05 to .01 =
greater confidence
24
8M Sickle cell anemia infection causes
encapsulated bacteria MOST COMMON: Strep pneumo N. meningitides + H. influ
25
Mitochondrial inheritance pattern --> what genetic variability
Heteroplasmy = normal + mutant genomes coexist on the same genome
26
68M persistent back pain metastatic cancer
Prostate cancer
27
RV vs LV
RV = 1. more collateral circulation 2. increased ischemic preconditioning 3. receives perfusion during systole & diastole
28
62M biopsy prostate might cause injury to
inferior hypogastric + splanchnic nerve = erectile dysfunction
28
Plasma concentration in reduced when
there is delayed absorption or high 1st pass metabolism
29
Mushroom toxin inhibits
Amatoxin inhibits RNA poly 2 = mRNA is inhibited
30
Synovial cell hyperplasia
RA
31
Fissuring & flaking of articular cartilage
OA
32
Poor night vision optic disc pallor areas of dark discoloration in retina attenuation of retinal vessels
Genetic progressive retinal dystrophy (pigmented epithelium + photoreceptors)= Retinitis pigmentosa
33
7M epistaxis BM = fat pancytopenia
Aplastic anemia
34
High FSH & LH Low testosterone Azoospermia
Klinefelter syndrome
35
Media grows= 1. round to oval budding yeast 2. germ tubes incubated a 37 C serum
Candida albicans = normal oral flora
36
Periductal lymphocytic infiltration of labial glands
Sjogren syndrome = dry people
37
32F 6 months of persistent diarrhea tea-colored odorless watery stools lack of gastric acid secretion Somatostatin relieves sx
Vasoactive Intestinal Peptide (VIP) = stimulates bicarbonate + chloride secretion (increase cAMP) = loss of Na+/Cl-/H2O Pancreatic islet cells = VIPoma
38
26F Swallows pills Pupils <2m Temp, BP, Tidal vol?
ALL LOW opioids causes hypothermia
39
Tx for manic features
Valproate + Carbamazepine + Lithium Lamotrigine = for depressive features
39
Which hyperlipidemia rx combination is more likely to cause myopathy
Statins + Fibrates Fibrates impair hepatic clearance of statins
40
54M splenomegaly pancytopenia dry tap dx
Hairy cell leukemia (lymphocytes w/ cytoplasmic projections)
41
Gerstmann syndrome affects
angular gyrus (dominant parietal lobe = usually Left)
42
How does Fibrates increase formation of cholesterol gallstones
inhibits 7a-hydroxlase Oxidases cholesterol & plays a role in bile synthesis
43
Vegans are at risk for which deficiencies
B12 & Iron
44
40F elevated Alkaline Phosphatase what should you check next
GGTP = biliary tract test
45
Difference between Clotrimazole vs Nystatin vs Mupirocin
All topicals Clotrimazole = dermatophytes Nystatin = Candida Mupirocin = Impetigo
46
Tinea pedis tx
microazole clotrimazole terbinafine tolnaftate
47
6hour drooling + coughing perioral cynosis
failure of foregut to separate from airway
48
Increase prevalence chances PPV and NPV by
increasing PPV and decrease NPV
Level 1/Step 1
flashcards
Decks in class (15)
# Cards
Brainscape helps you reach your goals faster, through stronger study habits.
© 2026 Bold Learning Solutions. Terms and Conditions