1
Q
How does Warfarin “Work”
A
inhibits enzyme that reduces oxidised Vitamin K
Cant participate in prothrombin activation.
2
Q
Clotting factors mechanism
A
- activation of prothrombin
- carboxylase
- Vitamin K is cofactor
- oxidised Vitamin K
- Warfarin inhibits reduction.
3
Q
Foods to avoid on Warfarin and WHY
A
Vitamin K food constituants = Kale, spinach
GREEN LEAFY VEG
Provide plenty of reduced vitamin K which will continue producing prothrombin = clotting factor.
4
Q
2 supplements to avoid on Warfarin
A
Vitamin K
Vitamin E - reduced production clotting factor prothrombin and thin blood even more.
