goal aPTT
1.5-2.5x contrl
aPTT is measured with what drug
heparin
HAT
HIT type 1
comes on quick
not immune
don’t need to stop heparin
mild decrease platelets (still > 100,000)
HIT
immune
7-14 days
platelets drop 50% or <100,000`
HIT management
stop heparin
lepirudin, bivalirudin, argatroban, fondaparinux
enoxaparin dose prophylaxis surgery pts
30mg Q12H
enoxaparin dose prophylaxis acute medical pts
40mg Q12H