What do we understand anesthesia to be
Sympathectomy
Def
Website: the cutting of clamping off of the sympathetic nerve chain. Keeps signals from passing through it
Modern history of Anesthesia
Name some individuals credited with discovery of inhaled anesthetics
Joseph Priestley- NO Crawford Long- Ether Horace Wells- NO William Morton- Gaseous Ether James Simpson- Chloroform
What assisted in their credit for discovering these anesthetics?
Documentation publishing, talking, etc
Alice Magaw
Known as Mother of Anesthesia
Agatha Hodgins
General Triad of Anesthesia
TRIANGLE
ED50 Dosing
Web: “median effective dose”= dose that produces quantal effect (all or nothing) in 50% of the population that takes it
-effective dose for 50% of people receiving drug
ED95
Web: dose required for desired effect in 95% of population exposed to it
Ex. Non- depolarizing agents= median dose required to achieve 95% reduction in maximal twitch response from baseline, in 50% of the population
Dyad of Regional Anesthesia
TRIANGLE with both at bottom points
Ex. Spinal/ Epidural …conditions for no pain,movement (abolition somatic/ Autonomic reflexes etc.
Local Anesthesia
-Anesthetic drug usu injected into tissue to numb specific location required for surgery
Regional
Ex. Epidural, Spinal, and PNB (peripheral nerve block)
-provides numbness to much larger area
MAC
General Anesthesia
- Usu requires assisted ventilation
Combination techniques
-MAC/sedation and Local/regional anesthesia, Regional. And general etc.
***MAC= Billing term
Anesthesia vs Sedation
Minimal Sedation
Moderate Sedation
Deep Sedation
General Anesthesia