Which chemo drug causes peripheral neuropathy (neurotoxicity)?
Vincristine. Rationale: Vincristine damages peripheral nerves → neuropathy, foot drop, constipation.
Which chemo drugs cause ototoxicity (tinnitus, hearing loss)?
Cisplatin, Carboplatin. Rationale: These platinum drugs damage the inner ear → hearing loss.
Which chemo drug causes cardiotoxicity (dilated cardiomyopathy)?
Doxorubicin, Daunorubicin. Rationale: Anthracyclines damage cardiac tissue; monitor lifetime dose.
Which chemo drugs cause pulmonary fibrosis?
Bleomycin, Busulfan. Rationale: Both can scar lung tissue; monitor for cough and dyspnea.
Which chemo drugs cause stomatitis/mucositis (mouth ulcers)?
Methotrexate, 5-FU. Rationale: Antimetabolites attack rapidly dividing mucosal cells.
Which chemo drugs cause hepatotoxicity?
Methotrexate, 6-Mercaptopurine. Rationale: Both metabolized in the liver → elevated AST/ALT.
Which chemo drugs cause nephrotoxicity (renal damage)?
Cisplatin, Carboplatin. Rationale: Platinum agents damage renal tubules; monitor creatinine, hydrate well.
Which chemo drugs cause hemorrhagic cystitis (bladder bleeding)?
Cyclophosphamide, Ifosfamide. Rationale: Toxic metabolite (acrolein) irritates bladder; Mesna prevents.
Which chemo drugs cause myelosuppression (bone marrow suppression)?
Most chemotherapy agents. Rationale: Affect rapidly dividing bone marrow cells → anemia, neutropenia, thrombocytopenia.
What is the main toxicity of vincristine?
Neurotoxicity (peripheral neuropathy). Rationale: Not bone marrow suppression like many others.
What is the main toxicity of cisplatin?
Nephrotoxicity and ototoxicity. Rationale: Damages kidneys and inner ear; hydrate and monitor labs.
What is the main toxicity of doxorubicin?
Cardiotoxicity. Rationale: Causes irreversible heart failure if cumulative dose is exceeded.
What is the main toxicity of bleomycin?
Pulmonary fibrosis. Rationale: Irreversible scarring of lung tissue.
What is the main toxicity of cyclophosphamide?
Hemorrhagic cystitis. Rationale: Bladder toxicity prevented with Mesna and hydration.
What nursing precaution prevents cisplatin nephrotoxicity?
Hydration and renal monitoring. Rationale: Flush drug through kidneys to reduce damage.
What nursing precaution prevents cyclophosphamide hemorrhagic cystitis?
Administer Mesna and encourage fluid intake. Rationale: Protects bladder lining.
Which chemo drug causes red urine and cardiotoxicity?
Doxorubicin. Rationale: Harmless red urine but dangerous cardiac toxicity; monitor ejection fraction.
Which chemo drug is most associated with severe mouth sores (mucositis)?
Methotrexate. Rationale: Antimetabolite toxic to oral mucosa.
Which chemo drug is most likely to cause pulmonary fibrosis with cough and dyspnea?
Bleomycin. Rationale: Monitor lung function and oxygenation.
Which labs should be monitored for methotrexate?
Liver function tests (AST, ALT) and CBC. Rationale: Risk of hepatotoxicity and myelosuppression.
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Week 1 Medications71
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week 1 lecture157
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Week 1 Chemo Man20
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week 2 cardiac anatomy and physiology of heart38
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Week 2 Cardiac91
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week 2 cardiac ATI115
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week 2 cardiac drugs120
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week 3 meds61
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week 3 lecture228
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week 3 ati157
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week 3 questions140
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midterm review94
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midterm medications180
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midterm neuro40
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week 6 endocrine135
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week 7177
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Final Exam154
