phenotype =
karyotype =
karyotype – pictorial view of chromosomes; tells number,
structure and sex
karyotype – 47 XY +21 (the +21 tells where the extra chromosome is)
phenotype – observable expressions of trait
autosomal dominant disorder -
what would each of these autosomes mean for this disorder
BB
Bb
bb
Has to have at least 1 big B for this disorder to happen
BB - disorder would happen
Bb - disorder would happen
bb - disorder would not happen
autosomal recessive disorder -
what would each of these autosomes mean for this disorder
BB
Bb
bb
Has to have bb for this disorder to happen
BB - disorder would not happen
Bb - would be an asymptomatic carrier
bb - disorder would happen
Umbilical cord
- Connects __ and __
- #__ arteries – carry ____
- # __ vein – carry ______
- Surrounded by _____
- sensory or motor innervation ?
- Twisted/spiral shape due ____
Umbilical cord
- Connects placenta and fetus
- 2 arteries – carry deoxygenated blood and waste from baby to placenta
- 1 vein – oxygenated blood from placenta to baby
- Surrounded by whartons jelly – connective tissue
- No sensory or motor innervation – no pain
- Twisted/spiral shape due to fetal movement
Decrease in normal vaginal flora (natural defense), bacteria overgrowth
Bacterial vaginosis
week 4
week 6
skin changes
hyper/hypo pigmentation
striae?
chloasma - what and where?
vascular spider nevi?
hair growth i/d
sweat and sebaceous glands i/d
linea nigra - what and where?
positive signs of pregnancy
Signs that are attributed only to the presence of the fetus, can only be caused by pregnancy
- Auscultation of fetal heartbeat
- Fetal movement
- Visualization of the fetus
detected in pregnancy test
hCG –
Enlarged ovaries, many small cysts along outer edge of ovaries
Polycystic ovarian syndrome
uterus changes
uterus size i/d____
fibrous tissue i/d____
blood flow i/d___
what type of contractions?
which way does uterus tilt when pregnant?
eye, cognitive, and metabolic changes
eye, cognitive, and metabolic
- decreased intraocular pressure
- cornea thickens
- decreased attention, concentration and memory
- extra water, fat, and protein are stored
- fats and more completely absorbed
week 36
Cause –
s/s – chancre, wart like lesion on vulva, fever, weight loss, malaise, painless
treatment –
Syphilis
Chronic infection from contact with open wound or acquired congenitally
Cause – spirochete treponema pallidum
s/s – chancre, wart like lesion on vulva, fever, weight loss, malaise, painless
treatment – penicillin
Most common STD
Chlamydial infection
Cause –
s/s – fever, rash on trunk looks like sunburn, vomit, hypotension, inflamed mucus membranes
treatment –
Toxic shock syndrome
Cause – toxin release by staph A
s/s – fever, rash on trunk looks like sunburn, vomit, hypotension, inflamed mucus membranes
treatment – hospitalization, IVF to maintain BP, antibiotics
Cause –
s/s – thin, purulent discharge, dysuria, lower abd pain
treatment –
Chlamydial infection
Most common STD
increases risk for PID
Cause – chlamydia trachomatis
s/s – thin, purulent discharge, dysuria, lower abd pain
treatment – azithromycin
breast changes
hyperplasia or hypertrophy
areolae darken/lighten
veins more/less prominent
striae
secretes what?
twins - identical (di/di, mono/di, mono/mono) vs fraternal (di/di)
Fraternal – di/di
cervix changes
mucous plug
goodells sign
chadwicks sign
hegards sign
what type of sign of pregnancy?
Amenorrhea
- n/v
- excessive fatigue
- urinary frequency
- breast changes
- quickening
presumptive
Changes experienced and reported by the woman that suggest the possibility of pregnancy but can also be caused by conditions other than pregnancy
Subjective
Dominant vs. Recessive Alleles:
2 copies needed
25% chance
only one copy needed
50% chance
Dominant vs. Recessive Alleles:
* Dominant: In autosomal dominant inheritance, only one copy of the altered gene (dominant allele) is needed from a parent to cause the trait or condition to appear in the offspring. 50%
* Recessive: In autosomal recessive inheritance, two copies of the altered gene (recessive allele) are needed, one from each parent, for the trait or condition to manifest. A normal gene (dominant allele) will mask the effect of the recessive allele. 25%