Hypothalamic-Pituitary-Thyroid axis
Hypothalamus: thyrotropin releasing hormone to –Pituitary: Thyroid stimulating hormone– Thyroid: thyroxine (T4) which is converted to triiodothyronine (T3)
Regulation of HPT axis
T3 and t4 will negatively feedback to pituitary and hypothathalmus
Primary hypothyroidism caused by dysfunction of?
Thyroid
Secondary hypothyroidism caused by dysfunction of?
Ant. Pituitary
Treatment options other than meds for graves
Surgery-reduction of thyroid gland
Tanner stages