Why do Infants Wheeze

Question 1

What is ‘wheeze’?

Answer 1

Wheeze originates from the intra-thoracic airways due to airway wall swelling and altered airway mechanics

Question 2

Define ‘stridor’

Answer 2

Obstruction of airway OUTSIDE of chest cavity, head more on INSPIRATION

Question 3

What is the difference between wheeze and stridor?

Answer 3

Wheeze = obstruction of lower respiratory tract heard more on EXPIRATION
Stridor = obstruction of airway OUTSIDE of chest cavity, head more on INSPIRATION

Question 4

How does asthma affect the airways on a cellular level?

Answer 4

> Goblet cell hyperplasia
Thickened sub-basement membrane
Cellular infiltrate

Question 5

What are bronchogenic cysts?

Answer 5

Have a thin wall with ciliated columnar lining which may contain cartilage and smooth muscle. Some have gastro-oesophageal mucosa and may be air or fluid-filled.