Williamson Ether Synthesis

Question 1

Contained the tylenol tablet: how did you characterize that you got the final product?

Answer 1

State the IR SPECTRUM

Question 2

Acetaminophen to phenacetin

Answer 2

Potassium carbonate
————->
Butanone

Question 3

N-H bond peak

Answer 3

3300-3600

Question 4

C=O bond peak

Answer 4

1600-1800

Question 5

O-H bond peak

Answer 5

3200-3600

Question 6

Williamson ether synthesis mechanism

Answer 6

SN2 reaction-2 steps

Question 7

First step in SN2

Answer 7

Deprotonate the alcohol with a BASE⚾️ to form an alkoxide ion(alcohol would be acetaminophen)

Deprot. OH-> Alkoxide

Question 8

Second Step in SN2

Answer 8

Produced alkoxide(nucleophile) -> reacts with the alkyl halide(electrophile) -> forms the ether phenacetin

Question 9

Alkoxide

Answer 9

O^-

Question 10

Melting point range of phenacetin

Answer 10

112-114 celsius

Question 11

Percent Recovery

Answer 11

Pure/Crude*100%