Work Up

Question 1

Required Imaging

Answer 1

1. Diagnostic CT scan of neck, chest, abdomen and pelvis
2. PET/CT scan
3. CXR

Question 2

When is an MR of head indicated?

Answer 2

1. CNS symptoms
2. Paranasal sinus involvement
3. Testicular involvement
4. Immunodeficiency

Question 3

What labs are needed?

Answer 3

1. CBC
2. BMP
3. LDH
4. LFTs including alkaline phosphatase
5. Pregnancy test in women of childbearing age
6. HIV test is patients with risk factors
7. Hepatitis B and C

Question 4

Who needs a Bone marrow biopsy?

Answer 4

All patients with NHL need a BM Bx

Question 5

Who needs an Llumbar puncture?

Answer 5

LP for CNS sx, testicular or paranasal sinus involvement or immunodeficiency

Question 6

What type of biopsy is needed to make the diagnosis?

Answer 6

Excisional biopsy of the palpable node

Question 7

Is DLBCL positive for CD20, CD5, or CD10?

Answer 7

CD20 +
CD5 -
CD 10 +