WT - Renal

Question 1

metabolic acidosis, how to check for compensation

Answer 1

pCO2=1.5(HCO3-)+/-2

Winter’s formula

Question 2

metabolic alkalosis, how to check for compensation

Answer 2

change in pCO2=0.7*(change in HCO3)

Question 3

RTA I

Answer 3

CD can’t excrete H+, thus can’t reabsorb K+
(ion change defect)

hypOK+

alkaline urine

via AI diseases, amphotericin B

Question 4

RTA II

Answer 4

dec reabsorb of HCO3 @ PCT

hypOK+

acidic urine

via acetazolamide, expired tetracylines

Question 5

RTA IV

Answer 5

dec response to aldo
impaired ammonium excretion (can’t synth NH3+)

hypERK+

acidic urine

via dec Aldo, K sparing diuretics, bacterium